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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Genome-wide DNA methylation analysis in precursor B-cells.
Published: December, 2014
Abstract: DNA methylation is responsible for regulating gene expression and cellular differentiation and for maintaining genomic stability during normal huma... Read more »
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DNA shearing Bioruptor
Foxk proteins repress the initiation of starvation-induced atrophy ...
Published: December, 2014
Abstract: Autophagy is the primary catabolic process triggered in response to starvation. Although autophagic regulation within the cytosolic compartment is ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq
Transcription bypass of DNA lesions enhances cell survival but atte...
Published: December, 2014
Abstract: Transcription-coupled DNA repair (TCR) is a subpathway of nucleotide excision repair (NER) dedicated to rapid removal of DNA lesions in the transcr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modif...
Published: December, 2014
Abstract: 5-hydroxymethylcytosine (5hmC) has been suggested to be involved in various nucleic acid transactions and cellular processes, including transcripti... Read more »
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Antibody H3pan (C15310135)
RAN-Binding Protein 9 is Involved in Alternative Splicing and is Cr...
Published: December, 2014
Abstract: As a member of the large Ran-binding protein family, Ran-binding protein 9 (RANBP9) has been suggested to play a critical role in diverse cellular ... Read more »
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Bioruptor Cell Lysis
Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine...
Published: December, 2014
Abstract: DNA glycosylases from the Fpg/Nei structural superfamily are base excision repair enzymes involved in the removal of a wide variety of mutagen and ... Read more »
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Bioruptor Cell Lysis Enzymatic Assay
Hypermethylation of cox5a promoter is associated with mitochondrial...
Published: December, 2014
Abstract: High-fat diet (HFD) is an environmental factor that contributes to the pathogenesis of obesity and type 2 diabetes. A number of genes influencing o... Read more »
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Antibody
Analysis of an artificial zinc finger epigenetic modulator: widespr...
Published: December, 2014
Abstract: Artificial transcription factors (ATFs) and genomic nucleases based on a DNA binding platform consisting of multiple zinc finger domains are curren... Read more »
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Antibody
Degradation of DNA damage-independently stalled RNA polymerase II i...
Published: December, 2014
Abstract: Transcription elongation is a highly dynamic and discontinuous process, which includes frequent pausing of RNA polymerase II (RNAPII). RNAPII compl... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Strategies for validation and testing of DNA methylation biomarkers.
Published: December, 2014
Abstract: DNA methylation is a stable covalent epigenetic modification of primarily CpG dinucleotides that has recently gained considerable attention for its... Read more »
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MethylCap
Predicting interactome network perturbations in human cancer: appli...
Published: December, 2014
Abstract: Genomic variations such as point mutations and gene fusions are directly or indirectly associated with human diseases. They are recognized as diagn... Read more »
Evaluation of methods to detect CALR mutations in myeloproliferativ...
Published: November, 2014
Abstract: The recent discovery of somatically acquired CALR mutations in a substantial proportion of patients with myeloproliferative neoplasms has provided ... Read more »
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DNA shearing Bioruptor
Natural genetic variation impacts expression levels of coding, non-...
Published: November, 2014
Abstract: Our current understanding of how natural genetic variation affects gene expression beyond well-annotated coding genes is still limited. The use of ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Regulation of anti-sense transcription by Mot1p and NC2 via removal...
Published: November, 2014
Abstract: The activity and dynamic nature of TATA-binding protein (TBP) crucial to RNA polymerase II-mediated transcription is under control of the Mot1p and... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Long non-coding RNA-mediated transcriptional interference of a perm...
Published: November, 2014
Abstract: Most long non-coding RNAs (lncRNAs) encoded by eukaryotic genomes remain uncharacterized. Here we focus on a set of intergenic lncRNAs in fission y... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic memory of the first cell fate decision prevents complete...
Published: November, 2014
Abstract: Embryonic (ES) and trophoblast (TS) stem cells reflect the first, irrevocable cell fate decision in development that is reinforced by distinct epig... Read more »
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DNA shearing Bioruptor
O-GlcNAcylation Prevents Aggregation of the Polycomb Group Represso...
Published: November, 2014
Abstract: The glycosyltransferase Ogt adds O-linked N-Acetylglucosamine (O-GlcNAc) moieties to nuclear and cytosolic proteins. Drosophila embryos lacking Ogt... Read more »
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Bioruptor Cell Lysis Western Blot
Cryptogenic stroke and small fiber neuropathy of unknown etiology i...
Published: November, 2014
Abstract: BackgroundFabry disease (FD) is a multisystemic disorder with typical neurological manifestations such as stroke and small fiber neuropathy (SFN), ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Synergistic template-free synthesis of dsDNA by Thermococcus nautil...
Published: November, 2014
Abstract: A combination of three enzymes from the hyperthermophilic archaeon Thermococcus nautili, DNA primase PolpTN2, DNA polymerase PolB, and pTN2 DNA hel... Read more »
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DNA shearing Bioruptor
MiR-98 delays skeletal muscle differentiation by downregulating E2F5.
Published: November, 2014
Abstract: A genome-wide screen had previously shown that knocking down miR-98 and let-7g, two miRNAs of the let-7 family, leads to a dramatic increase of ter... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesi...
Published: November, 2014
Abstract: Neuronal activity regulates the phosphorylation states at multiple sites on MeCP2 in postmitotic neurons. The precise control of the phosphorylatio... Read more »
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Bioruptor Cell Lysis
Regulatory network decoded from epigenomes of surface ectoderm-deri...
Published: November, 2014
Abstract: Developmental history shapes the epigenome and biological function of differentiated cells. Epigenomic patterns have been broadly attributed to the... Read more »
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DNA shearing Bioruptor
Single mutations in sasA enable a simpler ΔcikA gene network archit...
Published: November, 2014
Abstract: The circadian input kinase of the cyanobacterium Synechococcus elongatus PCC 7942 (CikA) is important both for synchronizing circadian rhythms with... Read more »
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DNA shearing Bioruptor
RNA helicase DDX21 coordinates transcription and ribosomal RNA proc...
Published: November, 2014
Abstract: DEAD-box RNA helicases are vital for the regulation of various aspects of the RNA life cycle, but the molecular underpinnings of their involvement,... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq
Concomitant downregulation of the imprinted genes DLK1 and MEG3 at ...
Published: November, 2014
Abstract: Background The two oppositely imprinted and expressed genes, DLK1 and MEG3, are located in the same gene cluster at 14q32. Previous studies in bla... Read more »
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True MicroChIP kit
Neuropeptide Y promotes adipogenesis in chicken adipose cells in vi...
Published: November, 2014
Abstract: Neuropeptide Y is an evolutionarily conserved neurotransmitter that stimulates food intake in higher vertebrate species and promotes adipogenesis i... Read more »
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Bioruptor Cell Lysis Enzymatic Assay Bioruptor Plus
Global methylation silencing of clustered proto-cadherin genes in c...
Published: November, 2014
Abstract: Epigenetic remodeling of cell adhesion genes is a common phenomenon in cancer invasion. This study aims to investigate global methylation of cell a... Read more »
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MeDIP kit
Circadian enhancers coordinate multiple phases of rhythmic gene tra...
Published: November, 2014
Abstract: Mammalian transcriptomes display complex circadian rhythms with multiple phases of gene expression that cannot be accounted for by current models o... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Identification by high-throughput imaging of the histone methyltran...
Published: November, 2014
Abstract: Recent evidence points to a role of chromatin in regulation of alternative pre-mRNA splicing (AS). In order to identify novel chromatin regulators ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Acute Depletion Redefines the Division of Labor among DNA Methyltra...
Published: November, 2014
Abstract: Global patterns of DNA methylation, mediated by the DNA methyltransferases (DNMTs), are disrupted in all cancers by mechanisms that remain largely ... Read more »
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Antibody 5mC (C15200081)

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