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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Sequence capture using PCR-generated probes: a cost-effective metho...
Published: March, 2014
Abstract: Recent advances in high-throughput sequencing library preparation and subgenomic enrichment methods have opened new avenues for population genetics... Read more »
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DNA shearing Bioruptor
Innate immune activity conditions the effect of regulatory variants...
Published: March, 2014
Abstract: To systematically investigate the impact of immune stimulation upon regulatory variant activity, we exposed primary monocytes from 432 healthy Euro... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Palindromic sequence artifacts generated during next generation seq...
Published: March, 2014
Abstract: Degradation-specific processes and variation in laboratory protocols can bias the DNA sequence composition from samples of ancient or historic orig... Read more »
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Microplex Library Preparation kit
Immune evasion by oncogenic proteins of acute myeloid leukemia.
Published: March, 2014
Abstract: PML-RARA and AML1-ETO are important oncogenic fusion proteins that play a central role in transformation to acute myeloid leukemia (AML). Whether t... Read more »
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Antibody
Citrullination regulates pluripotency and histone H1 binding to chr...
Published: March, 2014
Abstract: Citrullination is the post-translational conversion of an arginine residue within a protein to the non-coded amino acid citrulline. This modificati... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
RNAi screen in Drosophila larvae identifies histone deacetylase 3 a...
Published: March, 2014
Abstract: The transcription regulation of the Drosophila hsp70 gene is a complex process that involves the regulation of multiple steps, including the establ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
β-agonists selectively modulate proinflammatory gene expression in ...
Published: March, 2014
Abstract: The proinflammatory cytokine Tumour Necrosis Factor (TNF)-α is implicated in a variety of skeletal muscle pathologies. Here, we have investigated h... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Human-specific epigenetic variation in the immunological Leukotrien...
Published: March, 2014
Abstract: BACKGROUND: Common human diseases are caused by the complex interplay of genetic susceptibility as well as environmental factors. Due to the enviro... Read more »
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IP-Star
The transcription factor CREB has no non-redundant functions in hep...
Published: March, 2014
Abstract: AIMS/HYPOTHESIS: Excessive hepatic glucose production is a hallmark of insulin resistance in type 2 diabetes. The cAMP responsive transcription fac... Read more »
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Bioruptor Western Blot Tissue Homogenization
Polycomb binding precedes early-life stress responsive DNA methylat...
Published: March, 2014
Abstract: Early-life stress (ELS) in mice causes sustained hypomethylation at the downstream Avp enhancer, subsequent overexpression of hypothalamic Avp and ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K27me3 (C15410069)
A lipid-mediated conformational switch modulates the thermosensing ...
Published: March, 2014
Abstract: The thermosensor DesK is a multipass transmembrane histidine-kinase that allows the bacterium Bacillus subtilis to adjust the levels of unsaturated... Read more »
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Bioruptor
mMAPS: a flow-proteometric technique to analyze protein-protein int...
Published: March, 2014
Abstract: Signal transduction is a dynamic process that regulates cellular functions through multiple types of biomolecular interactions, such as the interac... Read more »
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DNA shearing Bioruptor
Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and at...
Published: March, 2014
Abstract: Genetic variation at the chromosome 9p21 risk locus promotes cardiovascular disease; however, it is unclear how or which proteins encoded at this l... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Contesting the dogma of an age-related heat shock response impairme...
Published: March, 2014
Abstract: Ageing is associated with the reduced performance of physiological processes and has been proposed as a major risk factor for disease. An age-relat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IPure kit
Peroxisome proliferator-activated receptor γ and C/EBPα synergistic...
Published: March, 2014
Abstract: Peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα) are key activators of ad... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
Promoter occupancy of the basal class I transcription factor A diff...
Published: March, 2014
Abstract: Monoallelic expression within a gene family is found in pathogens exhibiting antigenic variation and in mammalian olfactory neurons. Trypanosoma br... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Identification of HilD-regulated genes in Salmonella enterica serov...
Published: March, 2014
Abstract: Salmonella enterica serovar Typhimurium (S. Typhimurium) pathogenicity island 1 (SPI-1) encodes a type III secretion system required for invasion o... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Analysis of the SWI/SNF chromatin-remodeling complex during early h...
Published: March, 2014
Abstract: The regulatory networks of differentiation programs and the molecular mechanisms of lineage-specific gene regulation in mammalian embryos remain on... Read more »
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LowCell ChIP kit
SUMOylation of the polycomb group protein L3MBTL2 facilitates repre...
Published: March, 2014
Abstract: Lethal(3) malignant brain tumour like 2 (L3MBTL2) is an integral component of the polycomb repressive complex 1.6 (PRC1.6) and has been implicated ... Read more »
Principles of nucleation of H3K27 methylation during embryonic deve...
Published: March, 2014
Abstract: During embryonic development, maintenance of cell identity and lineage commitment requires the Polycomb-group PRC2 complex, which catalyzes histone... Read more »
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Antibody
SH2B1β interacts with STAT3 and enhances fibroblast growth factor 1...
Published: March, 2014
Abstract: Neurite outgrowth is an essential process during neuronal differentiation as well as neuroregeneration. Thus, understanding the molecular and cellu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Telomere repeat binding proteins are functional components of Arabi...
Published: March, 2014
Abstract: Although telomere-binding proteins constitute an essential part of telomeres, in vivo data indicating the existence of a structure similar to mamma... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Decreased genetic dosage of hepatic yin yang 1 causes diabetic-like...
Published: March, 2014
Abstract: Insulin sensitivity in liver is characterized by the ability of insulin to efficiently inhibit glucose production and fatty acid oxidation as well ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Extensive amplification of the E2F transcription factor binding sit...
Published: March, 2014
Abstract: Transposable elements (TEs) are major players in genome evolution. The effects of their movement vary from gene knockouts to more subtle effects su... Read more »
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Antibody LowCell ChIP kit
Transcription factor Runx3 regulates interleukin-15-dependent natur...
Published: March, 2014
Abstract: Natural killer cells belong to the family of innate lymphoid cells comprising the frontline defense against infected and transformed cells. Develop... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Sequential adaptive introgression of the mitochondrial genome in Dr...
Published: March, 2014
Abstract: Interspecific hybridization provides the unique opportunity for species to tap into genetic variation present in a closely related species and pote... Read more »
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DNA shearing Bioruptor
The transcriptional regulator Aire coopts the repressive ATF7ip-MBD...
Published: March, 2014
Abstract: The maintenance of immunological tolerance requires the deletion of self-reactive T cells in the thymus. The expression of genes encoding tissue-sp... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Minimal, encapsulated proteomic-sample processing applied to copy-n...
Published: March, 2014
Abstract: Mass spectrometry (MS)-based proteomics typically employs multistep sample-preparation workflows that are subject to sample contamination and loss.... Read more »
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Bioruptor Cell Lysis
Epigenetics of prostate cancer: distribution of histone H3K27me3 bi...
Published: March, 2014
Abstract: Prostate cancer is the second most common cause of cancer and the sixth leading cause of cancer fatalities in men world- wide (Ferlay et al., 2010)... Read more »
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IP-Star Antibody H3K27me3 (C15410069)
Stage-specific control of early B cell development by the transcrip...
Published: March, 2014
Abstract: The transcription factor Ikaros is an essential regulator of lymphopoiesis. Here we studied its B cell-specific function by conditional inactivatio... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K4me3 (C15410003)

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